Applied Sciences Research Periodicals <p><strong><em>Applied Sciences Research Periodicals (ASRP)</em></strong> is an open access and peer-reviewed international journal. It focuses on using scientific knowledge and principles to solve practical problems in real-world settings.</p> <p>ASRP covers multidisciplinary fields that encompasse a broad range of subjects, including engineering, technology, medicine, and agriculture, among others. The goal is to create innovative solutions to practical problems, improve existing technologies, and optimize processes to increase efficiency and productivity. Researcher in this field is aimed at working in collaboration with industry, government, and other stakeholders to translate scientific knowledge into practical applications that benefit society.</p> en-US (Faruk Soban) (Andrew Carr) Sat, 16 Mar 2024 15:02:59 +0000 OJS 60 Protective Effect of Zingiber Officinale Extract on Streptozotocin Induced Diabetes Mellitus in Mice <p>Spices, the predominant flavoring, coloring, and aromatic agents in food and beverages are now gaining importance for their diversified uses. Ginger (Zingiber Officinale) is a medicinal plant that has been widely used in Chinese, and Tibb Unani herbal medicines all over the world, since antiquity, for a wide array of unrelated ailments that include muscular aches, sore throat, constipation, arthritis, indigestion, vomiting and infectious diseases. Currently, there is a renewed interest in ginger, and several scientific investigations aimed at isolation and identification of active constituents of ginger, scientific verification of its pharmacological actions and of its constituents, and verification of the basis of the use of ginger in several diseases and conditions most common is use of ginger as complementary therapy in diabetes patients is now increasing due to less side effect comparing with antidiabetic drugs. Streptozotocin enter the B cell via glucose transporter (GLUT2)&nbsp; and cause alkylation of DNA. DNA damage induced by activation of poly ADP-ribosylation , a process is more important for diabetogenicity of streptpzotocin than DNA damage itself.&nbsp;</p> Samia Elzwi, Amina Elzwi Copyright (c) 2024 Samia Elzwi, Amina Elzwi Wed, 13 Mar 2024 00:00:00 +0000 Malaria Surveillance System Evaluation in Ankober Woreda North Shewa, Amhara Region, Ethiopia, 2022 <p><u>Background</u>: Malaria is a major public health concern worldwide, with the African region accounting for the majority of cases. Routine malaria surveillance data is crucial for assessing incidence and trends over time and detecting cases early for prompt management. The purpose of evaluating malaria surveillance systems is to assess how well they operate to meet their objectives and ensure efficient and effective monitoring of problems. This study aimed to evaluate and assess the performance of the existing malaria surveillance system and the status of surveillance attributes of malaria in Ankober woreda, North Shewa, Amhara. <u>General objective</u>: To evaluate and assess the performance of the existing Malaria surveillance system and the status of surveillance attributes of malaria in Ankober woreda, North Shewa, Amhara from December 16-26 2022. <u>Method</u>: A descriptive cross-sectional study were conducted from December 16-26, 2022. Ankober woreda were selected randomly among 239 malaria elimination targeted districts and total of nine health facilities were selected. The data were collected from surveillance officers in the selected health facilities using CDC surveillance system evaluation guideline check-list. <u>Result</u>: The results showed that case definitions were posted in all health centers, and understanding of them was good. The woreda reported a total of 26 confirmed malaria cases among 195 clinically suspected cases and zero deaths in 2014 EFY. The overall completeness and timeliness of the woreda surveillance for 2022 were 100% and 97%, respectively. Malaria epidemic monitoring charts were used to detect changes in cases but not analyzed by place and person. Irregular feedback and supportive supervision were conducted. High staff turnover and less trained and poorly incentivized health personnel with poor motivation and job satisfaction were found. The surveillance system was found to be useful, simple, flexible, acceptable, sensitive, and representative to all surveillance officers. <u>Conclusion</u>: Malaria surveillance system found to be satisfactory to achieve the intended objective of surveillance for public health action. Most surveillance system attributes are good.&nbsp; Working surveillance as an additional job and reduced training opportunity added with poor incentive mechanism will make low motivation and satisfaction with their job that definitely affect the stability of the system. The Malaria surveillance system presented in all assessed health institutions of Ankober woreda was found to be able to determine the magnitude of the disease for planning and intervention and detect change in malaria mortality and morbidity.</p> <p>&nbsp;</p> Tesfahun Abye, Bezawit Hailegiorgis, Bereket Taye, Tigist Abera Copyright (c) 2024 Tesfahun Abye, Bezawit Hailegiorgis, Bereket Taye, Tigist Abera Thu, 28 Mar 2024 00:00:00 +0000 Risk Factors For Hormone-Dependent Tumors: Breast And Prostate Cancer <p>It is a fact that gender- and hormone-dependent cancers are on the rise. This is no coincidence, but is due to a number of risk factors. These include: relative predominance of estrogens, xeno-estrogens especially in drinking water, intoxication by hydrocarbons and metals, radiation exposure, consequences of mRNA vaccinations, inadequate laboratory diagnostics with excessive normal ranges. Normal hormone levels in the blood should be aimed for individually; biochemical castration is an inadequate alternative. In order to avoid the negative developments, there is a selection of natural or nature-identical remedies (e.g. prohormones), which are listed below.</p> Doepp, Manfred Copyright (c) 2024 Doepp, Manfred Thu, 04 Apr 2024 00:00:00 +0100 The Disenchantment in Modern Physics <p>Isaac Newton looms over the Enlightenment as the giant who steered humanity out from under the dark shadows of superstition and into the bright, sterile light of the mechanical universe. Armed with the navigational tools of empirical evidence and mathematical proofs, he deciphered the forces of nature using human reason alone. With the publication of his masterwork Principia in 1687, the archaic belief in Nature’s soul was left shipwrecked on the shores of the unscientific past. Newton’s legacy is scientific positivism, or the belief that an idea is true only when it can be proved mathematically. If, in collective memory, René Descartes (1596-1650) succeeded in splitting the mind from the body, then Newton’s clockwork universe desacralized nature and cleaved the body from the soul. [43] At the end of 1918, Max Weber proclaimed at the University of Munich that ‘the fate of our times’ is the ‘disenchantment of the world’ The understanding that mystery and sacredness was disappearing from a world increasingly dominated by industry, science, and technology had its intellectual roots in German Romanticism, where it had found expression in the works of Novalis and Friederich Hölderlin. After Weber reintroduced the evocative term, “Entzauberung”, it would go on to have a deep impact on theories of modernity developed by the following generations.[44] Newton dressed his mystical intuition in mathematical proofs before presenting his ideas to the world. The father of mechanical science believed that spirit animated matter and his work was to understand, using the gifts of his meager human intellect, the eternal and divine. This article focusses on the “Prima Materia” described by Isaac Newton [43] and already thousands of years ago in “The Emerald Tablet of Hermes Trismegistus”. [45] In the Emerald Tablet, the “One Thing” refers to the “Prima Materia”. This was then acted upon by the thoughts or word of the One Mind to create the material reality we can observe with our senses. The fundamental concept of the “Prima Materia”” has been expressed in Equation (16) and (17) in which” Light” is the “Prima Materia” of our reality and the origin of our universe. Light is the building material out of which this universe has been created. The new theory, describing electro-magnetic-gravitational-acceleration force density interactions (expressed in N/m3), has been discussed at astronomical levels: Gravitational RedShift, Black Holes and Dark Matter and at sub-atomic levels: The absorption and emission of light at sub-atomic levels in concentric spheres by an atom at discrete energy levels. Evidence will be demonstrated about the correctness of this new electro-dynamic theory which represents the only theory which connects electro-dynamics in a correct way with plasma-dynamics. In general the gravitational (acceleration) force densities, originating from rotation and linear accelerations, are being ignored but with nuclear fusion processes these gravitational (acceleration) forces become fundamental and are necessary to develop a stable nuclear fusion process. Differently than in General Relativity, the electro-magnetic-gravitational-acceleration force density interactions (expressed in N/m3) [35] fundamentally has been based on the divergence of the sum of the “Stress Energy Tensor” and the introduced “Gravitational-Acceleration” Tensor. The theory describes “Gravitational-Acceleration-Electromagnetic” Interaction resulting in a mathematical Tensor presentation for BLACK HOLEs. (<strong>G</strong>ravitational <strong>E</strong>lectr<strong>o</strong>magnetic Co<strong>n</strong>finements) [1] The “Electromagnetic Energy Gradient” creates a second order effect “Lorentz Transformation” which results in the Gravitational Field of BLACK HOLEs which determines the interaction force density between the confinement of Light (BLACK HOLE’s) and the “Gravitational-Acceleration” Field. Einstein approached the interaction between gravity and light by the introduction of the “Einstein Gravitational Constant” in the 4-dimensional Energy-Stress Tensor (1). In this alternative approach related to General Relativity, the interaction between gravity and light has been presented by the sum of the Electromagnetic Tensor and the “Gravitational-Acceleration” Tensor (2) . The new theory describes the impact of "CURL" [38] within the gravitational fields around Black Holes and the impact on Gravitational Lensing. Gravitational "CURL" (Equation 6) is an effect which cannot be explained and calculated by General Relativity. The new approach presents mathematical solutions for the BLACK HOLEs (<strong>G</strong>ravitational <strong>E</strong>lectr<strong>o</strong>mag<strong>n</strong>etic Interaction) introduced in 1955 by Jonh Archibald Wheeler in the publication in Physical Review Letters in 1955 [1]. The mathematical solutions for BLACK HOLEs are fundamental solutions for the relativistic quantum mechanical Dirac equation (Quantum Physics) in Tensor presentation (41). Assuming a constant speed of light “c” and Planck’s constant ħ within the BLACK HOLE, the radius “R” of the BLACK HOLE with the energy of a proton, is about 1% of the radius of the hydrogen atom (14). The New Theory has been tested in an experiment with 2 Galileo Satellites and a Ground Station by measuring the Gravitational RedShift in an by the Ground Station emitted stable MASER frequency [2]. The difference between the calculation for Gravitational RedShift, within the Gravitational Field of the Earth, in “General Relativity” and the “New Theory” is smaller than 10<sup>-16 </sup>(12) and (13)<sup>. </sup><sup> </sup>In all “General Redshift Experiments” “General Relativity” and the New Electrodynamic-Gravitational-Acceleration” Theory predict a Gravitational RedShift with a difference smaller than 15 digits beyond the decimal point which is beyond the accuracy of modern “Gravitational Redshift” observations. Both values are always within the measured Gravitational RedShift in all observations being published since the first observation of the gravitational redshift in the spectral lines from the White Dwarf which was the measurement of the shift of the star Sirius B, the white dwarf companion to the star Sirius, by W.S. Adams in 1925 at Mt. Wilson Observatory. Theories which unify Quantum Physics and General Relativity [32], like “String Theory”, predict the non-constancy of natural constants. Accurate observations of the NASA Messenger [11] observe in time a value for the gravitational constant “G” which constrains until ( C' /G to be &lt; 4 × 10<sup>-14</sup> per year) . One of the characteristics of the New Theory is the “Constant Value” in time for the Gravitational Constant “G” in unifying General Relativity and Quantum Physics.</p> Wim Vegt Copyright (c) 2024 Wim Vegt Thu, 04 Apr 2024 00:00:00 +0100 When the Holiday Goes South: Case Study of Norovirus Outbreak and Overview of Common Food and Water Borne Illnesses <p>A recent outbreak of norovirus occurred approximately 24 hours into a cruise, while passengers were enroute to a Northern destination aboard a holiday cruise ship on a scheduled week-long journey. The symptoms of classic norovirus including watery diarrhea, severe abdominal cramps and nausea were quickly recognized, and the illness causation confirmed via on-board laboratory testing in the ship infirmary. Appropriate treatment prescribed by the ship’s physician, and containment was realized within a few days. Because of the limited number of passengers affected (12 out of over 1,000), and the timing of the incident, it was concluded that the origin of the infection likely occurred prior to or soon after the passengers boarded, possibly linked to a welcoming ceremony hosted by the ship’s captain during which a variety of h’odoerve style finger foods including some seafood items were made available during a buffet dinner. Following the initial outbreak, no additional cases were reported or identified, no on-board origin was confirmed, and all passengers recovered without incident and continued the cruise.</p> Vorachoat Karunyasopon, George P Einstein, Frantz Sainvil, Syed A. A. Rizvi, Orien L Tulp Copyright (c) 2024 Vorachoat Karunyasopon, George P Einstein, Frantz Sainvil, Syed A. A. Rizvi, Orien L Tulp Thu, 04 Apr 2024 00:00:00 +0100