Applied Sciences Research Periodicals https://hspublishing.org/ASRP <p><strong><em>Applied Sciences Research Periodicals (ASRP)</em></strong> is an open access and peer-reviewed international journal. It focuses on using scientific knowledge and principles to solve practical problems in real-world settings.</p> <p>ASRP covers multidisciplinary fields that encompasse a broad range of subjects, including engineering, technology, medicine, and agriculture, among others. The goal is to create innovative solutions to practical problems, improve existing technologies, and optimize processes to increase efficiency and productivity. Researcher in this field is aimed at working in collaboration with industry, government, and other stakeholders to translate scientific knowledge into practical applications that benefit society.</p> en-US office@headstartnetwork.org (Faruk Soban) asrp@hspublishing.org (Andrew Carr) Mon, 09 Nov 2026 06:37:41 +0000 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Farmer Organizations, Geographical Inequality and Access to Pluralistic Agricultural Extension Services in Bong County, Liberia https://hspublishing.org/ASRP/article/view/1800 <p><u>Background</u>: Farmer organizations can reduce the transaction costs of pluralistic extension delivery, but reliance on organized groups may leave non-members and some locations underserved. This study examined organizational and geographical inequalities in reported access to seven named extension providers in five districts of Bong County, Liberia. <u>Methods</u>: A cross-sectional survey used 232 records that mapped unambiguously to Fuamah, Jorquelleh, Kpai, Salala and Zota from a 326-record export. Access was defined as receipt from at least one named provider; plural and high access indicated two or more and four or more providers. Descriptive contrasts, chi-square tests, concentration indices and a robust logistic model were used. <u>Results</u>: Overall, 81.9% reported any access, 53.4% plural access and 18.5% high access. Members reported broader exposure than non-members: 60.8% versus 30.4% had plural access. Membership was associated with plural access, χ²(1) = 13.88, p &lt; .001, φ = .245; the unadjusted odds ratio was 3.47 (95% CI [1.81, 6.62]). In the stable adjusted model for any access, membership had an adjusted odds ratio of 5.83 (95% CI [2.35, 14.46]). District differences were pronounced: any access ranged from 38.5% in Kpai to 91.2% in Jorquelleh, while plural access ranged from 0.0% in Zota to 70.6% in Jorquelleh. Most providers’ reported recipients were highly geographically concentrated. <u>Conclusion</u>: Farmer organizations appear to be important bridges into the pluralistic service system, but group-based delivery and programme geography can jointly reproduce exclusion. Parallel non-member outreach, district service mapping and transparent eligibility rules are recommended.</p> James Kamara, Mohamed Paul Ngegba, Leroy Wanga Cegbe Copyright (c) 2026 James Kamara, Mohamed Paul Ngegba, Leroy Wanga Cegbe http://creativecommons.org/licenses/by/4.0 https://hspublishing.org/ASRP/article/view/1800 Mon, 09 Nov 2026 00:00:00 +0000 The Effects of Aging, Epigenetic Expression, and Obese Phenotype on Parameters of Glycemic Status, Glucose Oxidation, Insulin Resistance and Adiposity in the Congenic LA/Ntul//-cp Rat https://hspublishing.org/ASRP/article/view/1858 <p>Pathophysiologic manifestations of systemic Insulin resistance (IR) in association with obesity and overweight conditions are a common observation in man and animals. The purpose of the current investigation was to determine the characteristics of adiposity, IR, and insulin-stimulated glucose oxidation (ISGOX) in diaphragm muscle in normally reared and fed aging female congenic, lean and obese LA/Ntul//-<em>cp</em> rats from 4 to 24 months of age. Insulin resistance&nbsp; (IR) in the diaphragm muscle is a condition where the muscle under fixed glucose concentrations may become less responsive to insulin, thereby impairing glucose uptake and potentially contributing to progressive diaphragmatic weakness and respiratory dysfunction. Thus, IR may become&nbsp; a contributor to insulin resistance in muscle and adipose tissue depots particularly in conditions like obesity and obesity linked comorbidities including type 2 diabetes (T2DM/NIDDM).&nbsp; While peripheral skeletal musculature groups often represent a primary locale of IR in man and animals, the ongoing physiologic contractile activity of the diaphragm muscle may escape much of the&nbsp; early impact of IR since it remains a more physiologically active muscle group than skeletal muscle groups throughout the lifespan in man and animals, and thus may confer a measure of metabolic protection from more extensive features of IR. Groups of lean and obese female littermate LA/Ntul//-<em>cp </em>rats,&nbsp; a rodent model where epigenetic obesity occurs independently of NIDDM were studied at 4, 14, and 24 months of age. Parameters of adiposity, IR and ISGOX in diaphragm muscle were determined in the presence or absence of insulin (100 µU/ml; medium glucose 10 mM).&nbsp; Relative adiposity was computed by the addition of the sum of dorsal and retroperitoneal adipose tissue depots as a proportion of final body weight.&nbsp;&nbsp; Body weight of lean animals was similar at all ages studied, while body weight of obese rats increased further at each successive age studied. Fasting plasma glucose concentrations were similar in both phenotypes at all ages studied, but plasma insulin concentrations and the insulin:glucose ratios, established biomarkers of IR, &nbsp;were markedly elevated in the obese phenotype, with only modest age-related improvement. Measures of basal and ISGOX in diaphragm were consistent&nbsp; with age related decreases in baseline and insulin-stimulated glucose oxidation in the lean phenotype. In contrast, baseline and ISGOX in the obese phenotype were consistent with IR. These results suggest that the capacity for insulin-stimulated glucose oxidation and energy metabolism decreased by advances in aging in this muscle group in concert with progressive increases in adiposity with aging.</p> Orien L Tulp Copyright (c) 2026 Orien L Tulp http://creativecommons.org/licenses/by/4.0 https://hspublishing.org/ASRP/article/view/1858 Mon, 09 Nov 2026 00:00:00 +0000